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Breast milk probiotic delays skin ageing


Probiotics reportedly interfere with skin aging and the development of atopic dermatitis, allergic rhinitis, and wound healing in rodents​ and humans​. Although the details of the mechanism by which oral probiotics improve skin condition are unclear, some researchers​ have proposed that it may involve the restoration of the pH value of the skin to its normal range and the inhibition of protease activity in aged skin possibly by inhibiting inflammatory activities.

Studies​ have shown that S​. thermophilus​ produces various types of extracellular polysaccharides (responsible for the skin’s natural ability to hydrate and retain water), and treatment with S​. thermophilus​ was able to induce an increasing ceramide level (waxy lipid molecules which lock moisture into the skin) in healthy subjects and atopic dermatitis patients​, and could produce hyaluronic acid (HA​, a key molecule in skin aging).

In the current study, researchers from Taiwan aimed to explore whether S​. thermophilus​ improved skin aging using the probiotic TCI633 (5 × 108 live Streptococcus thermophiles​; 400 mg per capsule) isolated from breast milk. 

The study

The team recruited thirty subjects and randomly assigned them to the intervention or placebo group. Participants were told to take two tablets a day for eight weeks.

The fasting blood of each participant was collected at weeks 0 and 8. The levels of the serum biochemical parameters including Hyaluronic acid (HA), Superoxide Dismutase (SOD), and catalase were monitored. Other parameters in serum, including the levels of cholesterol, triglyceride, serum glutamate oxaloacetate transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), blood urine nitrogen (BUN), uric acid, and creatinine were monitored. 

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